Inhibitors of Electron Transport Chain
Most of the friends answered wrongly in the quiz.Don't forget ! Fo is not F zero. O is for Oligomycin.
It is my duty to put a small note on ETC inhibitors as this topic is very important for exams.
Amobarbital & Rotenone --> Complex I (NADH dehydrogenase-CoQ.)
Rotenone and MPTP (a neuro-toxin) --> Inhibits complex I and causes Parkinsons like features
Antimycin A - inhibits --> Complex III (Q-cytochrome c oxidoreductase)
H2S, CO & Cyanide --> inhibits complex IV (Cytochrome Oxidase)
Oligomycin --> inhibits Fo component of ATP synthase
Atractyloside --> inhibits Translocase
Thermogenin --> brown adipose tissue,physiological uncoupler
Thyroxine
Dinitrophenol --> uncoupler
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